Fromtheir discovery, antibiotics have significantly improved clinical treatments of infections,\nthus leading to diminishing morbidity and mortality in critical care patients, as well as surgical,\ntransplant and other types of medical procedures. In contemporary medicine, a significant debate\nregarding the development of multi-drug resistance involves all types of pathogens, especially in\nacute care hospitals due to suboptimal or inappropriate therapy. The possibility of nanotechnology\nusing nanoparticles as matrices to encapsulate a lot of active molecules should increase drug efficacy,\nlimit adverse effects and be an alternative helping to combat antibiotic resistance. The major\naim of this study was to obtain and to analyze physico-chemical features of chitosan used as a\ndrug-delivery system in order to stop the antibiotic resistance of different pathogens. It is well\nknown that World Health Organization stated that multidrug resistance is one of the most important\nhealth threats worldwide. In last few years, nano-medicine emerged as an improved therapy to\ncombat antibiotic-resistant infections agents. This work relies on enhancement of the antimicrobial\nefficiency of ceftriaxone against.......................
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